Discrimination of N6-methyl adenine in a specific DNA sequence.
نویسندگان
چکیده
We have developed a novel chemistry-based method to detect adenine methylation. A DNA probe functionalized with a formyl group discriminates between adenine and N6-methyl adenine by the formation of a selective interstrand cross-link.
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 30 شماره
صفحات -
تاریخ انتشار 2010